The mission of the Mississippi Safe Schools Coalition is to ensure that all students have a safe learning environment by protecting students’ constitutional rights, ending homophobia, transphobia, sexism, and all forms of discrimination, and fostering acceptance of LGBT students through public education and advocacy.

The GSA of USM is very active at USM and in Hattiesburg.

The University of Mississippi Gay-Straight Alliance (GSA) is a student organization that provides LGBT advocacy and education.